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Analysis of 16 Y-chromosomal STRs in an African descent sample population of Chocó (Colombia)
Authors:J.J. Builes,N. Alzate,C. Espinal,L. Gusmã  o
Affiliation:a GENES Ltda., Laboratorio de Genética Forense y Huellas Digitales del DNA, Medellín, Colombia
b Instituto de Biología, Universidad de Antioquia, Medellín, Colombia
c Instituto Nacional de Medicina Legal y Ciencias Forenses, Medellín, Colombia
d IPATIMUP, Instituto de Patologia e Imunologia Molecular da Universidade do Porto, Porto, Portugal
Abstract:We studied and established a database and some parameters of forensic importance were calculated of 16 Y-STR (DYS19, DYS385, DYS389I/II, DYS390, DYS391, DYS392, DYS393, DYS437, DYS438, DYS439, DYS460, DYS461, GATA-A10, GATA-H4 and DYS635) in a population of 298 unrelated males of African descent of Chocó (Colombia) and a total of 257 haplotypes were identified using the present set of Y-STR markers, of which 224 were represented only once in the database. Twenty-six haplotypes were presents two times, six haplotypes were presents in three individuals and one haplotype in four men. The haplotype diversity was 0.9987 ± 0.0004. By combining the allelic states of the 16 Y-chromosomal STRs we could construct highly informative haplotypes that allowed the discrimination of 86.2% of the samples tested. With this work we established a database of Y-STR and some parameters of forensic importance. This approach represents a very powerful tool for individual identification and paternity testing in forensic genetic.
Keywords:Chocó     Y-chromosome   STR   Population   Colombia
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