| 尸体脏器中安定、利眠宁及其代谢降解产物的毛细柱GC/MS鉴定 |
| |
| 引用本文： | 李玉兰,何毅,徐婉. 尸体脏器中安定、利眠宁及其代谢降解产物的毛细柱GC/MS鉴定[J]. 中国法医学杂志, 1992, 0(4) |
| |
| 作者姓名： | 李玉兰 何毅 徐婉 |
| |
| 作者单位： | 公安部第二研究所毒化室，公安部第二研究所毒化室，公安部第二研究所毒化室 北京 100038，北京 100038，北京 100038 |
| |
| 摘 要： | 本文描述了尸体脏器中安定、利眠宁及其代谢降解产物二苯甲酮类、N-去甲安定、舒宁和脱氧利眠宁的毛细柱GC/MS鉴定方法,讨论了热解和代谢过程。
|
| 关 键 词： | 安定 利眠宁 代谢降解产物 GC/MS鉴定 |
THE IDENTIFICATION OF DIAZEPAM, CHLORDIAZEPOXIDE AND THEIR MAJOR METABOLITES IN URINE AND POSTMORTEM TISSUES BY CAPILLARY COLUMN GC/MS |
| |
| Li Yulan He Yi Xu Wan Institute of Forensic Science,Ministry of public Security,Beijing. THE IDENTIFICATION OF DIAZEPAM, CHLORDIAZEPOXIDE AND THEIR MAJOR METABOLITES IN URINE AND POSTMORTEM TISSUES BY CAPILLARY COLUMN GC/MS[J]. Chinese Journal of Forensic Medicine, 1992, 0(4) |
| |
| Authors: | Li Yulan He Yi Xu Wan Institute of Forensic Science Ministry of public Security Beijing |
| |
| Affiliation: | Li Yulan He Yi Xu Wan Institute of Forensic Science,Ministry of public Security,Beijing,100038 |
| |
| Abstract: | This paper describes an analytical method that can be used to identify diazepam, chlordiazepoxide and theirs major metabolites, N-desoxydemoxepam, 2-amino-5-chlorobenzophenons, oxazepam, desoxychlordiazepoxide, in the postmortem tissues and urine. The sample was extracted using ethyl ether at PH 9-10, and repurified by TLC, final analysed by GC/MS or direct solid probe on the Finnigan mat 1020GC/MS. The detection limit ,1s 15 ng for chlordiazepoxide and diazemap. This paper discusses the process of heat degradation and metabolism. |
| |
| Keywords: | Diazepam Chlordiazepoxide Metabolites GC/MS identification |
| 本文献已被 CNKI 等数据库收录！ |
|
