结蛋白诊断早期心肌梗死的特异性研究

目的 探讨结蛋白在早期心肌梗死死后诊断的特异性。方法 应用免疫组织化学Ｓ－Ｐ法检测梗死心肌和其他非梗死性的直接或间接心肌损害的心肌结蛋白染色的变化。结果 梗死心肌均可见不同程度的结蛋白缺染，其他非梗死性的直接或间接心肌损害的心肿，如心脏挫伤、心肌炎、出血性休克、电击死、机械性窒息、有机磷中毒等，也有不同程度的结蛋白缺染。 结论 应用结蛋白免疫组织化学方法诊断早期心肌梗死需慎重。

Study on the specificity of desmin for the diagnosis of early myoc ardial infarction

Objective　To explore the specificity of desmin (D m) in the postmo rtem diagnosis of early myocardial infarction. Methods　The cha nges of Dm stainin g in the infarcted myocardium and other non-infarcted myocardium with direct or indirect myocardial injury, such as cardiac contusion, myocarditis, hemorrhagic shock, electrocution, mechanical asphyxia and organophosphate poisoning, were st udied with immunohistochemical S-P method. Results The loss of Dm staining in d i fferent degrees was found in the infarcted myocardium, but the change of loss of Dm staining was also seen in the other non-infarcted myocardium with direct or indirect myocardial injury, Conclusion　It should be cautious t o diagnose early myocardial infarction with Dm immunohistochemisrty.