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化痰通瘀解毒方对S180小鼠移植瘤微血管密度及血管内皮生长因子表达的影响
引用本文:黄金玲,王桐生,王训翠,王靓,蔡横,桑方方,刘先华. 化痰通瘀解毒方对S180小鼠移植瘤微血管密度及血管内皮生长因子表达的影响[J]. 安徽中医药大学学报, 2011, 30(2): 52-54
作者姓名:黄金玲  王桐生  王训翠  王靓  蔡横  桑方方  刘先华
作者单位:安徽中医学院,安徽,合肥,230038;合肥市妇幼保健所,安徽,合肥,230061
基金项目:安徽省高等学校自然科学研究项目
摘    要:目的 探讨化痰通瘀解毒方抑制肿瘤微血管生成作用的机制.方法 复制小鼠S180移植瘤模型,采用免疫组织化学法观察化痰通瘀解毒方对肿瘤微血管密度(micro-vessel density,MVD)及血管内皮生长因子( vascular endothelial growth factor,VEGF)的影响.结果与模型组比较,...

关 键 词:化痰通瘀解毒方  S180  移植瘤  微血管密度  血管内皮生长因子

Effects of Huatan Tongyu Jiedu Recipe on Expression of Microvessel Density and Vascular Endothelial Growth Factor in Mice Bearing S180 Transplanted Tumor
HUANG Jin-ling,WANG Tong-sheng,WANG Xun-cui,WANG Liang,CAI Heng,SANG Fang-fang,LIU Xian-hua. Effects of Huatan Tongyu Jiedu Recipe on Expression of Microvessel Density and Vascular Endothelial Growth Factor in Mice Bearing S180 Transplanted Tumor[J]. Journal of Anhui Traditional Chinese Medical College, 2011, 30(2): 52-54
Authors:HUANG Jin-ling  WANG Tong-sheng  WANG Xun-cui  WANG Liang  CAI Heng  SANG Fang-fang  LIU Xian-hua
Affiliation:HUANG Jin-ling1,WANG Tong-sheng1,WANG Xun-cui1,WANG Liang1,CAI Heng2,SANG Fang-fang1,LIU Xian-hua1(1.Anhui College of Traditional Chinese Medicine,Anhui Hefei 230038,China,2.Hefei Maternity and Child Health Care Center,Anhui Hefei 230061,China)
Abstract:Objective To explore the mechanism of Huatan Tongyu Jiedu(HTJ) Recipe,a traditional Chinese prescription for removing phlegm,activating blood circulation and detoxicating,in inhibiting the angiogenesis of tumor microvessels.Methods The model of S180 transplanted tumor was induced in mice.An immunohistochemical method was employed to observe the effects of HTJ Recipes on the expression of microvessel density(MVD) and vascular endothelial growth factor(VEGF).Results The expression levels of MVD and VEGF were ...
Keywords:S180
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