PCR-based detection of HLA-DQ alpha and polymarker loci and their application in forensic science |
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Authors: | Lin Y Que T Li L Zhao Z |
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Affiliation: | Institute of Forensic Sciences, Ministry of Justice, Shanghai, 200063. |
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Abstract: | Studies were conducted to evaluate the forensic applicability of multiplex amplification of HLA-DQ alpha and PM loci. These loci could be simultaneously typed by reverse dot blot approach where allele specific oligonucleotide probes were immobilized on a nylon membrane strip. Allele and genotype frequencies for HLA-DQ alpha and PM loci were determined in Chinese Han population. The frequency data can be used in individual identification and paternity test. |
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