| 过敏性休克死亡者肺组织类胰蛋白酶及类糜蛋白酶的表达 |
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| 引用本文： | 卫志燕,高彩荣,裴明. 过敏性休克死亡者肺组织类胰蛋白酶及类糜蛋白酶的表达[J]. 法医学杂志, 2009, 25(3): 164-167. DOI: 10.3969/j.issn.1004-5619.2009.03.002 |
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| 作者姓名： | 卫志燕 高彩荣 裴明 |
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| 作者单位： | 山西医科大学法医学院法医病理学教研室,山西,太原,030001 |
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| 摘 要： | 目的观察类胰蛋白酶与类糜蛋白酶在过敏性休克死亡人体肺组织中的表达，并探讨其在过敏性休克死亡法医学鉴定中的意义。方法应用荧光免疫组化法对类胰蛋白酶与类糜蛋白酶进行检测，同时以10例CO中毒死者为对照：采用图像分析仪及Image—pro plus 5．0．2软件进行图像分析，计算阳性肥大细胞数及类胰蛋白酶、类糜蛋白酶荧光表达强度。结果与对照组相比，实验组肺组织中类胰蛋白酶和类糜蛋白酶表达差异有统计学意义（P〈0．05）。结论过敏性休克死亡人体肺组织中类胰蛋白酶与类糜蛋白酶的表达增强．可作为过敏性休克死亡的形态学诊断依据。
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| 关 键 词： | 法医病理学 过敏反应 肺 类胰蛋白酶类 糜蛋白酶类 |
Expression of Tryptase and Chymase in Human Lung Tissue of Anaphylactic Shock |
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| WEI Zhi-yan,GA Cai-rong,PEI Ming. Expression of Tryptase and Chymase in Human Lung Tissue of Anaphylactic Shock[J]. Journal of Forensic Medicine, 2009, 25(3): 164-167. DOI: 10.3969/j.issn.1004-5619.2009.03.002 |
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| Authors: | WEI Zhi-yan GA Cai-rong PEI Ming |
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| Affiliation: | WEI Zhi-yan,GAO Cai-rong,PEI Ming(Department of Forensic Pathology,School of Forensic Medicine,Shanxi Medical University,Taiyuan 030001,China) |
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| Abstract: | Objective To explore the expression of tryptase and chymase in human lung tissue of anaphylactic shock and its value for forensic medicine.Methods With ten carbon monoxide poisoning cases as control group,the levels of tryptase and chymase were observed by immunofluorescence and analyzed using the Image Analyze and the Image-pro plus 5.0.2.The positive mast cells were counted and the levels of the tryptase and chymase were calculated respectively.Results There was a statistically significant difference(P<0.... |
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| Keywords: | forensic pathology anaphylaxis lung tryptases chymases |
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