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针刺对腹部术后胃肠功能恢复及胃肠激素分泌的影响
作者姓名:黄龙  于庆生  潘晋方  帅剑锋  梁久银  张琦  刘举达  王振  周富海
作者单位:安徽中医药大学第一附属医院普外科安徽省中医药科学院中医外科研究所,安徽合肥,230031;安徽中医药大学第一附属医院普外科安徽省中医药科学院中医外科研究所,安徽合肥,230031;安徽中医药大学第一附属医院普外科安徽省中医药科学院中医外科研究所,安徽合肥,230031;安徽中医药大学第一附属医院普外科安徽省中医药科学院中医外科研究所,安徽合肥,230031;安徽中医药大学第一附属医院普外科安徽省中医药科学院中医外科研究所,安徽合肥,230031;安徽中医药大学第一附属医院普外科安徽省中医药科学院中医外科研究所,安徽合肥,230031;安徽中医药大学第一附属医院普外科安徽省中医药科学院中医外科研究所,安徽合肥,230031;安徽中医药大学第一附属医院普外科安徽省中医药科学院中医外科研究所,安徽合肥,230031;安徽中医药大学第一附属医院普外科安徽省中医药科学院中医外科研究所,安徽合肥,230031
基金项目:安徽中医药大学青年科学研究基金项目(2014qn021);“十二五”国家临床重点专科建设项目(财社〔2013〕239号)
摘    要:目的 观察针刺对腹部术后胃肠功能的恢复作用及其对胃肠激素分泌的影响。方法 将100例行腹部外科手术患者随机分为研究组及对照组,每组50例。两组患者均接受外科常规治疗,研究组加用针刺疗法,疗程7 d。治疗后分别观察两组患者胃肠功能恢复情况,采用放射免疫法测定血清胃泌素及血浆生长抑素和血浆胃动素水平。结果 与对照组比较,研究组患者术后肛门排气时间、排便时间、肠鸣音恢复时间、拔除胃管时间、进食时间均明显缩短(P<0.05)。与对照组比较,研究组血清胃泌素水平显著降低,血浆生长抑素和胃动素水平显著升高(P<0.05)。两组并发症发生率比较,差异均无统计学意义(P>0.05)。结论 针刺对腹部外科术后患者胃肠功能的恢复作用与其调节胃肠激素分泌有关。

关 键 词:胃泌素  生长抑素  胃动素  胃动力  胃肠激素

Effects of Acupuncture on Recovery of Gastrointestinal Function and Gastrointestinal Hormone Secretion after Abdominal Surgery
Institution:1.Department of General Surgery, The First Hospital Affiliated to Anhui University of Chinese Medicine & Institute of Chinese Traditional Surgery, Anhui Academy of Chinese Medicine, Anhui Hefei 230031, China
Abstract:Objective To investigate the effects of acupuncture on recovery of gastrointestinal function and gastrointestinal hormone secretion after abdominal surgery. Methods One hundred patients who received abdominal surgery were randomly and equally divided into acupuncture group and control group. Patients in both groups received conventional therapy, and patients in the acupuncture group received acupuncture therapy in addition. The treatment lasted for 7 days. The recovery of gastrointestinal function after treatment was observed in each group. Levels of serum gastrin, plasma somatostatin, and plasma motilin were determined using radioimmunoassay. Results Compared with the control group, the acupuncture group had significantly shortened postoperative time to first flatus, first defecation, first bowel sound, extubation, and first eating (P<0.05). Moreover, the acupuncture group had a significantly lower level of serum gastrin and significantly higher levels of plasma somatostatin and motilin compared with the control group (P<0.05). There was no significant difference in the incidence of complications between the two groups (P>0.05). Conclusion The impacts of acupuncture on recovery of gastrointestinal function after abdominal surgery are associated with the regulation of gastrointestinal hormone secretion.
Keywords:gastrin  somatostatin  motilin  gastric motility  gastrointestinal hormone
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