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c-jun及其表达产物的法医学应用前景
引用本文:刘雁军,张天林,王英元. c-jun及其表达产物的法医学应用前景[J]. 法律与医学杂志, 2007, 14(1): 79-82
作者姓名:刘雁军  张天林  王英元
作者单位:山西医科大学法医学院 太原030001(刘雁军,王英元),山西省晋城市公安局技术处 048000(张天林)
基金项目:山西省教育厅事业发展专项基金(200558)
摘    要:c-jun基因是即刻早期基因jun家族成员之一,正常情况下该基因在大多数细胞中表达水平很低且不易被检测到,但在外界某些因素作用下,可被快速激活使之明显表达,其表达产物在多种基因表达、细胞增殖、细胞分化、凋亡等过程中起重要作用。本文综述了即刻早期基因c-jun及其产物c-jun蛋白的结构特点、生物学功能,着重从脊髓损伤、颅脑枪弹创、电击伤等方面阐述了其法医学应用。

关 键 词:即刻早期基因  c-jun  法医学
文章编号:1007-9297(2007)01-0000-00
修稿时间:2006-10-30

Forensic application prospect of immediately early gene c-jun and its products.
LIU Yan-jun,ZHANG Tian-lin,WANG Ying-yuan.School of Forensic Medicine,Shanxi Medical University,Taiyuan. Forensic application prospect of immediately early gene c-jun and its products.[J]. The Journal of Law & Medicine, 2007, 14(1): 79-82
Authors:LIU Yan-jun  ZHANG Tian-lin  WANG Ying-yuan.School of Forensic Medicine  Shanxi Medical University  Taiyuan
Affiliation:LIU Yan-jun,ZHANG Tian-lin,WANG Ying-yuan.School of Forensic Medicine,Shanxi Medical University,Taiyuan 030001
Abstract:c-jun gene is a member of IEGs(Immediately Early Genes) jun.In the normal condition,it is in the low expression stage and cannot be detected.But it can be activated by many factors strongly and rapidly,and its products play an important role on gene expression,cell proliferation,cell differentiation and apoptosis.This paper explores on the construction features and biological function of the c-jun gene and its products.We also explain its forensic application in spinal injury,electric shock injury,and so on.
Keywords:Immediately Early Genes  c-jun  forensic medicine
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