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Subaortic Pseudoaneurysm of the Left Ventricle Complicating Staphyloccal Endocarditis*
Authors:Pauline Saint‐Martin M.D.  Christopher Rogers M.D.  Eugene Carpenter M.D.  Michael C. Fishbein M.D.   Ph.D.  Stanley Lau M.D.
Affiliation:1. Service de Médecine Légale, H?pital Trousseau, Centre Hospitalier Régional Universitaire de Tours, 37?044 Tours Cedex 1, France.;2. Department of Coroner, Los Angeles County, 1104 North Mission Road, Los Angeles, CA 90033.;3. Department of Pathology and Laboratory Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095.;4. Southern California Heart Center, 506 West Valley Boulevard, Suite 100, San Gabriel, CA 91776.
Abstract:Abstract: Subaortic pseudoaneurysms are rare but can be a cause of sudden death in young individuals. This case report involves a 20‐year‐old Vietnamese male who died suddenly from rupture of a subaortic pseudoaneurysm with resultant hemopericardium with tamponade. He had a history of bicuspid aortic valve with recent but healed Staphylococcal endocarditis. A review of the literature reveals few similar cases and enlightens the association between aortic bicuspid valve, endocarditis, and subvalvular aortic aneurysm. The pathogenesis as well as recent studies that identified aneurysm predisposing genes in patients with bicuspid aortic valve will be discussed.
Keywords:forensic science  forensic pathology  pseudoaneurysm  endocarditis  aortic valve  mycotic aneurysm
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