Y-chromosome STR haplotypes in Sweden |
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| Authors: | Holmlund Gunilla Nilsson Helena Karlsson Andreas Lindblom Bertil |
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| Affiliation: | 1. Cardiovascular Institute, University of Manchester, Manchester, UK;2. Central Manchester Foundation Trust, Manchester, UK;3. School of Medicine & Dentistry, University of Aberdeen, Foresterhill, Aberdeen, UK;4. Cardiovascular Institute, University of Manchester, Manchester, UK;5. Norwich Medical School, University of East Anglia, Norwich, UK;1. Faculty of Civil Engineering, Brno University of Technology, Veveří 331/95, 602 00 Brno, Czech Republic;2. Department of Geological Sciences, Faculty of Science, Masaryk University, Kotlářská 267/2, 611 37 Brno, Czech Republic |
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| Abstract: | A total of 708 men, with Swedish names, from different parts of Sweden have been typed for the Y-chromosome minimal haplotype STR markers DYS19, DYS389I, DYS389II, DYS390, DYS391, DYS392, DYS393 and DYS385. Of these, 403 men were of geographically undefined Swedish origin and the rest, 305, from seven defined geographical regions. PCR-products were detected by ABI377 using sequenced allelic ladders. An evaluation of the 708 chromosomes revealed 423 different haplotypes. Only 100 of the haplotypes were found more than once. The over all haplotype diversity was 0.994. The haplotype 14, 12, 28, 23, 10, 11, 13, 14-14 has the highest frequency of 5.79% and is significantly Swedish, when compared to other European populations. |
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