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| 尿中五氯酚和2.4-二氯-6-硝基苯酚气相色谱分析 | |
| 引用本文： | 陈祥国,姜兆林,王淑真,张银华,吕纪忠. 尿中五氯酚和2.4-二氯-6-硝基苯酚气相色谱分析[J]. 中国法医学杂志, 2011, 26(3): 213-215 |
| 作者姓名： | 陈祥国 姜兆林 王淑真 张银华 吕纪忠 |
| 作者单位： | 1. 湖北省公安厅刑侦总队,湖北武汉,430070 2. 中国刑事警察学院刑技四系,辽宁沈阳,110035 3. 武汉市医疗救治中心,湖北武汉,430023 |
| 摘 要： | 目的建立利用气相色谱分析检测尿中五氯酚和2，4-二氯-6-硝基苯酚的方法。方法取空白尿液添加五氯酚和2.4-二氯-6-硝基苯酚标准品及内标2.4-二氯苯酚，经乙酸酐衍生化后，采用气相色谱法进行检测，并对提取方法、衍生化条件等进行考察。结果经气相色谱分析，尿中五氯酚和2.4-二氯-6-硝基苯酚可得到有效分离，无杂质干扰且峰形较好。在pH值为2条件下，以环己烷作为萃取溶剂为最佳萃取条件。衍生化优选条件为使用10灿乙酸酐并加入10μL无水吡啶，60℃反应30min。结论采用气相色谱法检测尿中五氯酚和2.4-二氯-6-硝基苯酚，方法简单、结果准确，可在实际办案中应用。 |
| 关 键 词： | 法医毒物分析 乙酰化 五氯酚 2.4-二氯-6-硝基苯酚 |
Determination of pentachlorophenol and 2,4-dichloro-6-nitrophenol in urine by gas chromatography |
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| CHEN Xiangguo,JIANG Zhaolin,WANG Shuzhen,ZHANG Yinhua,LV Jizhong. Determination of pentachlorophenol and 2,4-dichloro-6-nitrophenol in urine by gas chromatography[J]. Chinese Journal of Forensic Medicine, 2011, 26(3): 213-215 | |
| Authors: | CHEN Xiangguo JIANG Zhaolin WANG Shuzhen ZHANG Yinhua LV Jizhong |
| Affiliation: | CHEN Xiangguo1,JIANG Zhaolin2,WANG Shuzhen3,ZHANG Yinhua1,LV Jizhong1/1.Department of Public Security of Hubei Province,Wuhan 430070,China,2.China Criminal Police University,Shenyang 110035,3.Wuhan Medical Treatment Center,Wuhan 430023 |
| Abstract: | Objective A method for the detection of pentachlorophenol and 2,4-dichloro-6-nitrophenol in urine by gas chromatography was developed.Methods After derivatized with acetic anhydride,pentachlorophenol,2,4-dichloro-6-nitrophenol and 2,4-dichlorophenol in blank urine were determined accurately by gas chromatography.The effects of several important factors,such as the methods of extraction and conditions of derivative were investigated.Results By using gas chromatography,pentachlorophenol and 2,4-dichloro-6-nit... |
| Keywords: | forensic toxicological analysis acetylation pentachlorophenol 2 4-dichloro-6-nitrophenol |
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