| 类胰蛋白酶及其法医学应用 |
| |
| 引用本文： | 刘丹,刘良,周亦武. 类胰蛋白酶及其法医学应用[J]. 中国法医学杂志, 2005, 20(1): 41-43 |
| |
| 作者姓名： | 刘丹 刘良 周亦武 |
| |
| 作者单位： | 1. 武汉科技大学医学院病理教研室,湖北,武汉,430080;华中科技大学同济医学院法医学系,湖北,武汉,430030
2. 华中科技大学同济医学院法医学系,湖北,武汉,430030 |
| |
| 摘 要： | 类胰蛋白酶由肥大细胞表达,以活性形式储存在肥大细胞的脱颗粒中。作为肥大细胞及其脱颗粒的标志,类胰蛋白酶具有多种生物活性,可以促进气道的恢复,调节气道平滑肌细胞的张力和反应性,提高毛细血管的通透性,刺激新生血管的生成,进而启动和加速多种疾病的进程,并与过敏反应、羊水拴塞、注射海洛因过量、外伤致死及SIDS等有关,因而在法医学中有重要的意义。
|
| 关 键 词： | 法医学 类胰蛋白酶(TS) 肥大细胞(MC) 疾病 |
| 文章编号： | 1001-5728(2005)01-0041-03 |
| 修稿时间： | 2003-11-01 |
Tryptase and the application in forensic medicine |
| |
| Affiliation: | (LIU Dan,LIU Liang,ZHOU Yi-wu Department of Pathology,College of Medical Science,Wuhan University of Science and Technology,Wuhan 430080,China) |
| |
| Abstract: | Tryptases are expressed in most human mast cells, and stored in a fully enzymatically active state in mast cells secretory granules. As the marker of mast cell activation, tryptases have many biological functions, for example, contributing to airway remodeling, modulating airway smooth muscle tone and response, activating mast cells, raising capillaries permeability, stimulating proliferation of tumor blood vessel, and so on. They seem to be relevant to the occurrence and development of many diseases, such as allergic reaction, amnionic fluid embolism, poisoning by heroin and SIDS. So they have important value in forensic medicine. |
| |
| Keywords: | Forensic medicine Tryptase Mast cell Disease |
| 本文献已被 CNKI 万方数据 等数据库收录！ |
|
