| 采用自主研发似然比率计算器进行ITO亲缘关系分析 |
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| 引用本文： | 周密,张韩秋,韦帆,丁仁杰,王成权. 采用自主研发似然比率计算器进行ITO亲缘关系分析[J]. 中国法医学杂志, 2011, 26(5): 365-367 |
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| 作者姓名： | 周密 张韩秋 韦帆 丁仁杰 王成权 |
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| 作者单位： | 芜湖市公安局刑警支队,安徽芜湖,241000 |
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| 摘 要： | 目的探讨采用自主研发的似然比率计算器进行ITO法亲缘关系鉴定的可行性。方法针对GoldeneyeTMDNA ID System 20A系统的19个常染色体STR基因座分型数据,使用自主研发的似然比率计算器,人工模拟100 000对无关个体及100 000个家系的父子、同胞、半同胞、一、二代堂表兄弟,应用ITO法,自动分析计算亲权指数（PI）和亲缘关系概率（RCP）。结果父子和无关个体关系概率界值下无重叠,具有显著差异。同胞关系概率大于99.99%时,同胞占66.48%,无关个体占0%,具有显著差异;概率小于99.99%时,同胞个体和无关个体有部分重叠,具有一定差异。半同胞关系概率大于99.99%时,半同胞占1.52%,无关个体占0%,具有显著差异;概率小于99.99%时,两组有部分重叠,具有一定差异。一、二代堂表兄弟关系概率为10%～90%范围内时,无关个体分别占90%,99.98%,无法推断。结论本文方法可用于推断父子关系、同胞关系、半同胞关系。
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| 关 键 词： | 法医物证学 亲缘鉴定 ITO法 似然比率计算器 |
Analysis of genetic relationship with ITO method using selfdeveloped likelihood ratio calculator |
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| ZHOU Mi,ZHANG Hanqiu,WEI Fan,DING Renjie,WANG Chengquan. Analysis of genetic relationship with ITO method using selfdeveloped likelihood ratio calculator[J]. Chinese Journal of Forensic Medicine, 2011, 26(5): 365-367 |
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| Authors: | ZHOU Mi ZHANG Hanqiu WEI Fan DING Renjie WANG Chengquan |
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| Affiliation: | (ZHOU Mi,ZHANG Hanqiu,WEI Fan,DING Renjie,WANG Chengquan/Wuhu Public Security Bureau,Anhui Wuhu 241000,China) |
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| Abstract: | Objective To evaluate the feasibility of genetic relationship analysis with ITO method using selfdeveloped likelihood ratio(LR) calculator.Methods For the typing data of 19 autosomal STR loci with the GoldeneyeTM DNA ID System 20A,the paternity index(PI) and relative chance of paternity(RCP) of 100 000 pairs of unrelated individuals,parent-child,full-sibling,halfsibling,first cousin,and second cousin from manual simulation were automatically analyzed with ITO method using selfdeveloped likelihood ratio(LR) ... |
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| Keywords: | forensic biological evidence relationship identification ITO method LR calculator |
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