| 大鼠弥漫性轴索损伤后海马热休克蛋白质70mRNA表达 |
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| 引用本文： | Wang F,Li YH. 大鼠弥漫性轴索损伤后海马热休克蛋白质70mRNA表达[J]. 法医学杂志, 2011, 27(4): 250-252. DOI: 10.3969/j.issn.1004-5619.2011.04.003 |
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| 作者姓名： | Wang F Li YH |
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| 作者单位： | 皖南医学院法医学系,安徽芜湖,241001 |
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| 摘 要： | 目的 研究大鼠弥漫性轴索损伤(diffuse axonal injury,DAI)后大脑海马中热休克蛋白质(heat-shockproteins,HSP)70 mRNA的表达变化.方法 采用RT-PCR扩增,扩增产物用琼脂糖凝胶电泳检验,观察DAI后大鼠海马中HSP70 mRNA的表达变化.结果 损伤后4h,大鼠海马中...
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| 关 键 词： | 法医病理学 弥漫性轴索损伤 海马 HSP70热休克蛋白质类 大鼠 |
Expression of HSP70 mRNA in hippocampus of rats after diffuse axonal injury |
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| Wang Feng,Li Yong-Hong. Expression of HSP70 mRNA in hippocampus of rats after diffuse axonal injury[J]. Journal of Forensic Medicine, 2011, 27(4): 250-252. DOI: 10.3969/j.issn.1004-5619.2011.04.003 |
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| Authors: | Wang Feng Li Yong-Hong |
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| Affiliation: | WANG Feng,LI Yong-hong(Department of Forensic Medicine,Wannan Medical College,Wuhu 241001,China) |
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| Abstract: | Objective To explore the changes of expression of heat-shock proteins(HSP) 70 mRNA in hippocampus of rats after diffuse axonal injury(DAI).Methods RT-PCR products of HSP70 mRNA were tested by agarose gel electrophoresis after RT-PCR amplification.The changes of HSP70 mRNA expression were observed in rat hippocampus after DAI.Results The expression of HSP70 mRNA in the hippocampus could be detected 4 h after DAI.It reached maximum at 24 h and declined after 48 h.Conclusion HSP70 mRNA in hippocampus of rats c... |
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| Keywords: | forensic pathology diffuse axonal injury hippocampus HSP70 heat-shock proteins rats |
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