| 胸膜肺炎放线杆菌感染对猪肺及肺门淋巴结抗氧化功能的影响 |
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| 引用本文： | 左之才,崔恒敏,彭西,王娅,邓俊良,徐志文,甘梦. 胸膜肺炎放线杆菌感染对猪肺及肺门淋巴结抗氧化功能的影响[J]. 中国兽医科学, 2012, 0(7): 713-718 |
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| 作者姓名： | 左之才 崔恒敏 彭西 王娅 邓俊良 徐志文 甘梦 |
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| 作者单位： | 四川农业大学动物医学院 环境公害与动物疾病四川省高校重点实验室 动物疫病与人类健康四川省重点实验室 |
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| 基金项目： | 教育部“长江学者和创新团队发展计划”创新团队项目(IRT0848);四川省教育厅重点资助项目(08ZA055) |
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| 摘 要： | 将24头健康DLY(杜洛克×长白×约克夏)仔猪按性别、体重随机分为2组,采用鼻腔喷雾法分别接种生理盐水(对照组)和含3.8×107 CFU/mL胸膜肺炎放线杆菌的稀释液(试验组),研究了猪感染胸膜肺炎放线杆菌48h后血清及肺组织抗氧化功能的变化。结果显示,试验组血清中SOD、CAT的含量极显著低于对照组(P<0.01);GSH-Px、MDA含量极显著高于对照组(P<0.01);-OH含量显著高于对照组(0.010.05)。试验组肺组织除CAT含量显著高于对照组(0.01
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| 关 键 词： | 猪 胸膜肺炎放线杆菌 抗氧化功能 肺 淋巴结 |
Effect of Actinobacillus pleuropneumoniae infection on the antioxidant function of lung and tracheobronchial lymph node in pigs |
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| ZUO Zhi-cai,CUI Heng-min,PENG Xi,WANG Ya,DENG Jun-liang,XU Zhi-wen,GAN Meng. Effect of Actinobacillus pleuropneumoniae infection on the antioxidant function of lung and tracheobronchial lymph node in pigs[J]. Chinese Veterinary Science, 2012, 0(7): 713-718 |
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| Authors: | ZUO Zhi-cai CUI Heng-min PENG Xi WANG Ya DENG Jun-liang XU Zhi-wen GAN Meng |
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| Affiliation: | (Key Laboratory of Animal Disease and Human Health of Sichuan Province/Key Laboratory of Environmental Hazard and Animal Diseases of Sichuan Province/College of Veterinary Medicine, Sichuan Agricultural University,Ya’an 625014 China) |
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| Abstract: | To examine the effect of Actinobacillus pleuropneumoniae(APP) infection on the antioxidant function of serum and the lung tissue in pigs,24 healthy DLY(Duroc×Landrace×Yorkshire)piglets were randomly divided into two groups by gender and body weight inoculated with physiological saline(control group) and the diluent contained 3.8×107 CFU/mL APP serotypeⅠ(treatment group) by atomizing inhalation in each nostril,respectively.Compared with those of the control group,it was found that in the treatment group,the serumal superoxide dismutase(SOD) and catalase(CAT) contents decreased(P<0.01),and the total antioxidant capacity(T-AOC) decreased(P>0.05);while the glutathione peroxidase(GSH-Px) and malonaldehyde(MDA) contents increased(P<0.01),and the serumal hydroxyl radical(-OH) content increased(0.01
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| Keywords: | pig Actinobacillus pleuropneumoniae antioxidant function lung lymph node |
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