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连接蛋白43与心性猝死的相关性研究进展
引用本文:程灵犀,罗斌,林俊莲,刘水平,阳宇,汪冠三,许心舒,张能培,韩奇杰. 连接蛋白43与心性猝死的相关性研究进展[J]. 中国法医学杂志, 2009, 24(3): 179-181
作者姓名:程灵犀  罗斌  林俊莲  刘水平  阳宇  汪冠三  许心舒  张能培  韩奇杰
作者单位:1. 中山大学中山医学院法医学系,广东,广州,510080
2. 广州市公安局刑事科学技术研究所,广东,广州,510030
摘    要:部分心性猝死者死后尸检时心脏没有发现明显病理学异常征象,过去均将其归属原因不明的猝死范畴。近年来研究显示,心肌连接蛋白43(connexin43,Cx43)表达对于心性猝死的诊断具有十分重要的意义。本文就Cx43结构、功能以及在心血管疾病发生发展中的作用与法医学意义作一综述。

关 键 词:法医病理学  连接蛋白43  心血管疾病  心性猝死

An overview of the relationship between connexin43 and sudden cardiac death
CHENG Lingxi,LUO Bin,LIN Junlian,LIU Shuiping,YANG Yu,WANG Guansan,XU Xinshu,ZHANG Nengpei,HAN Qijie. An overview of the relationship between connexin43 and sudden cardiac death[J]. Chinese Journal of Forensic Medicine, 2009, 24(3): 179-181
Authors:CHENG Lingxi  LUO Bin  LIN Junlian  LIU Shuiping  YANG Yu  WANG Guansan  XU Xinshu  ZHANG Nengpei  HAN Qijie
Affiliation:CHENG Lingxi,LUO Bin~1,LIN Junlian~2,LIU Shuiping~1,YANG Yu~1,WANG Guansan~2,XU Xinshu~2,ZHANG Nengpei~1,HAN Qijie~1/1.Department of Forensic Pathology,Zhongshan School of Medicine,Sun Yat-sen University,Guangzhou 510080,China,2.Guangzhou Criminal Science & Technology Institute,Guangzhou 510030
Abstract:No evidence of pathological abnormalities of the heart is found in some sudden heart death by postmortem autopsy.This kind of sudden death is classified as being of unknown aetiology.Recently, some studies have showed that basic structure,function and the role of connexin43(Cx43) for diagnosing sudden cardiac death are of great significance.
Keywords:forensic pathology  connexin43  cardiovascular disease  sudden heart death  
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