| X—STR基因座的法医学应用研究进展 |
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| 引用本文： | 曾祥培,李海霞,孙宏钰. X—STR基因座的法医学应用研究进展[J]. 中国司法鉴定, 2010, 0(1): 58-62. DOI: 10.3969/j.issn.1671-2072.2010.01.016 |
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| 作者姓名： | 曾祥培 李海霞 孙宏钰 |
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| 作者单位： | 中山大学中山医学院法医物证教研室,广州,510089 |
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| 基金项目： | 国家自然科学基金，教育部留学回国人员科研启动基金 |
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| 摘 要： | 对X染色体的结构特征、遗传特征及其短串联重复序列（STR）基因座在法医学领域的研究历史、现状进行了综述。并分析了X染色体STR基因座在混合斑鉴定和复杂亲子关系鉴定中的应用，以及在法医学领域应用中应注意的问题．如单倍型和连锁不平衡现象等。
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| 关 键 词： | 法医遗传学 X染色体 短串联重复序列 |
The Research Progress of X Chromosome STR Loci in Forensic Genetics |
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| ZENG Xiang-pei,LI Hai-xia,SUN Hong-yu. The Research Progress of X Chromosome STR Loci in Forensic Genetics[J]. Chinese Journal of Forensic Sciences, 2010, 0(1): 58-62. DOI: 10.3969/j.issn.1671-2072.2010.01.016 |
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| Authors: | ZENG Xiang-pei LI Hai-xia SUN Hong-yu |
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| Affiliation: | ZENG Xiang-pei,LI Hai-xia,SUN Hong-yu (Department of Forensic Medicine,Zhongshan School of Medicine,Sun Yat-sen University,Guangzhou 510089,China) |
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| Abstract: | This article summarizes the structure and hereditary characteristics of X chromosome and the history and present situation of X-chromosome specific short tandem repeat (X-STR) loci in forensic medicine. The application of X-STR loci in mixed stain identification and complex paternity cases is discussed. Some problems which should been paid attention to when using X -chromosome STR loci in forensic medicine are also proposed,such as the haplotyping and linkage disequilibrium phenomena. |
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| Keywords: | forensic genetics X chromosome short tandem repeat (STR) |
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