The microscopic pathology of the liver in fatal cocaine intoxication |
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Authors: | A R Copeland |
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Affiliation: | 1. Department of Pharmaceutical Sciences, University of Colorado Center for Pharmaceutical Biotechnology, Aurora, Colorado 80045;2. Malvern Instruments Ltd., Amesbury, Wiltshire SP4 7RT, UK;1. Department of Nanotechnology, Agricultural Biotechnology Research Institute of Iran (ABRII), Agricultural Research, Education and Extension Organization (AREEO), Karaj, Iran;2. Soil Science Department, College of Agriculture and Natural Resources, University of Tehran, Karaj, Iran;3. Tea Research Center, Horticultural Sciences Research Institute, Agricultural Research, Education and Extension Organization (AREEO), Lahijan, Iran;4. Department of Soil Biology, Soil and Water Research Institute, Agricultural Research, Education and Extension Organization (AREEO), Karaj, Iran;1. Department of Chemical Engineering, Science and Research Branch, Islamic Azad University, Tehran, Iran;2. Center of Excellence in Electrochemistry, School of Chemistry, College of Science, University of Tehran, Tehran, Iran;3. Department of Nutrition, Cihan University-Erbil, Kurdistan Region, 625 Erbil, Iraq;4. Department of Phytochemistry, SRC, Soran University, 624 KRG, Iraq;5. Department of Polymer Technology, Faculty of Chemistry, Gdańsk University of Technology, G. Narutowicza 11/12 80-233, Gdańsk, Poland;6. Department of Chemical Engineering, Amirkabir University of Technology (Tehran Polytechnic), Tehran, Iran;7. College of Engineering and Technology, American University of the Middle East, Kuwait;8. Department of Physics, Sharif University of Technology, P.O. Box 11155-9161, Tehran, Iran;9. School of Engineering, Macquarie University, Sydney, New South Wales 2109, Australia;10. Department of Materials Science and Engineering, Pohang University of Science and Technology (POSTECH), 77 Cheongam-ro, Nam-gu, Pohang, Gyeongbuk 37673, South Korea;11. Department of Inorganic Chemistry, Faculty of Chemistry and Petroleum Sciences, Shahid Beheshti University, P. O. Box 19839-63113, Tehran, Iran;12. Biomaterial Group, Department of Biomedical Engineering, Amirkabir University of Technology, Tehran, Iran;13. Department of Mechanical Engineering, National University of Singapore, 117575, Singapore;14. Departamento de Química Orgánica, Universidad de Córdoba, Campus de Rabanales, Edificio Marie Curie (C-3), Ctra Nnal IV-A, km 396, Cordoba 14014, Spain;1. Institute of Engineering Thermophysics, Chinese Academy of Sciences, Beijing 100190, China;2. Department of Micro and Nanofabrication, International Iberian Nanotechnology Laboratory, Av. Mestre José Veiga s/n, 4715-330 Braga, Portugal;3. Department of Petroleum, Universiti Teknologi PETRONAS, 32610 Bandar Seri Iskandar, Perak, Malaysia;4. Department of Chemical Engineering, Faculty of Engineering, University of Malaya, Kuala Lumpur, Malaysia;5. University of Chinese Academy of Sciences, Beijing 100049, China |
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Abstract: | The microscopic pathology of the liver in fatal cocaine intoxication was studied. Data from cases of cocaine intoxication during the years 1981-1986 were collected and analysed. Thirty cases with a negative past history for intravenous drug abuse, and in which the terminal drug testing revealed solely cocaine or its metabolites, were compared with a control group of nineteen people who had died in motor vehicle accidents, with a terminal negative blood alcohol, negative drug screen and no history of drug abuse. A comparison of liver histology was made along with gross anatomical liver weight. These findings are compared to other studies of hepatotoxicity in drug abuse. |
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