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| 猪离体心脏冠状动脉的MSCT造影 | |
| 引用本文： | 万雷,特来提·赛依提,魏华,应充亮,王亚辉,邓恺飞,邹冬华,李正东,朱广友.猪离体心脏冠状动脉的MSCT造影[J].法医学杂志,2014,30(5):321-324. |
| 作者姓名： | 万雷 特来提·赛依提 魏华 应充亮 王亚辉 邓恺飞 邹冬华 李正东 朱广友 |
| 作者单位： | 1. 司法部司法鉴定科学技术研究所上海市法医重点实验室,上海,200063 2. 新疆警察学院侦察系,新疆乌鲁木齐,830011 3. 司法部司法鉴定科学技术研究所上海市法医重点实验室,上海200063;华东政法大学研究生教育院,上海200042 |
| 基金项目： | 国家自然科学基金资助项目，中央级科研院所科研专项，“十二五”国家科技支撑计划项目，上海市法医学重点实验室资助项目 |
| 摘 要： | 目的 通过对猪离体心脏冠状动脉进行多层螺旋CT（MSCT）造影成像,探索离体心脏血管造影技术的具体操作方法及参数.方法 应用自主改装的血管造影装置,分别将脂溶性和水溶性对比剂以不同灌注量（50、60、70 mL）和不同灌注-成像时间间隔（5、10、20 min）灌注猪离体心脏冠状动脉,进行MSCT扫描和三维图像效果比较,由2名放射科医生对各组的造影成像效果进行评估和记录,并对结果进行统计学分析. 结果 脂溶性对比剂对冠状动脉周围脂肪造成浸润和破坏而影响造影成像效果,而水溶性对比剂未出现类似结果.灌注-成像时间间隔为5 min,且灌注量为60 mL和70 mL时造影成像质量最佳. 结论 本研究的血管造影参数为后期开展尸体在体心脏冠脉造影奠定基础. |
| 关 键 词： | 法医病理学 血管造影 虚拟解剖 对比剂 冠状动脉 |
Coronary Angiography of in vitro Porcine Heart Using MSCT |
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| Institution: | WAN Lei, TaloT＇SIYI, WEI Hua, YING Chong-liang, WANG Ya-hui, DENG Kai-fei, ZOU Dong- hua, LI Zheng-dong, ZHU Guang-you (1. Shanghai Key Laboratory of Forensic Medicine, Institute of Forensic Science, Ministry of Justice, P.R.Chi- no, Shanghai 200063, China; 2. Faculty of Reconnaissance, Xinjiang Police College, Urumqi 830011, Chi- na; 3. Graduate School of East China University of Political Science and Law, Shanghai 200042, China) |
| Abstract: | Objective To establish standardized methods and parameters of the isolated heart coronary an- giography through the experiment of in vitro porcine heart by MSCT. Methods Based on different perfu- sion volume （50, 60 and 70mL） and different perfusion-imaging time （5, 10 and 20min）, the in vitro porcine coronary artery was injected liposoluble and water-soluble contrast agents using remodel angiog- raphy equipment and scanned by MSCT. And the 3D image results were compared. The images were recorded and evaluated by 2 radiologists and analyzed by statistical soft-ware. Results Liposoluble con- trast agent affected the images by damaging and infiltrating the fats around the coronary artery, while the water-soluble contrast agent didn＇t affect the images. The groups with 60 mL or 70 mL perfusion and 5 min perfusion-imaging time had the best images. Conclusion The suitable parameters of the an- giography lay the foundation of postmortem coronary angiography. |
| Keywords: | forensic pathology angiography virtopsy contrast agents coronary |
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