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| 大鼠急性心肌缺血动物实验模型的改进 | |
| 引用本文： | Luo B,Xiang L,Jiang DH,Kong XP,Zhang NP,He Y,Zhang B,Yang Y,Cheng LX. 大鼠急性心肌缺血动物实验模型的改进[J]. 法医学杂志, 2006, 22(5): 321-323 |
| 作者姓名： | Luo B Xiang L Jiang DH Kong XP Zhang NP He Y Zhang B Yang Y Cheng LX |
| 作者单位： | 1. 中山大学基础医学院法医系,广东,广州,510080 2. 山东大学齐鲁医院病理科,山东,济南,250012 3. 中山大学肿瘤医院医务科,广东,广州,510080 4. 泰安市公安局,山东,泰安,250012 |
| 基金项目： | 国家自然科学基金资助项目(39700167) |
| 摘 要： | 目的改进大鼠急性心肌缺血动物实验模型时,提高手术的成功率和动物成活率。方法比较传统方法与改进方法动物试验的成功率。结果传统方法成功率只有60%,改进方法成功率达到90%以上。结论改进后的方法能大大降低手术难度,减少实验费用,优于传统方法。 |
| 关 键 词： | 大鼠 心肌缺血 动物实验模型 |
| 文章编号： | 1004-5619(2006)05-0321-03 |
| 修稿时间： | 2005-12-20 |
Improved method of acute myocardial ischemic rat model |
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| Luo Bin,Xiang Lei,Jiang Dong-Hua,Kong Xiao-Ping,Zhang Neng-Pei,He Yun,Zhang Bin,Yang Yu,Cheng Ling-Xi. Improved method of acute myocardial ischemic rat model[J]. Journal of Forensic Medicine, 2006, 22(5): 321-323 | |
| Authors: | Luo Bin Xiang Lei Jiang Dong-Hua Kong Xiao-Ping Zhang Neng-Pei He Yun Zhang Bin Yang Yu Cheng Ling-Xi |
| Affiliation: | Department of Forensic Medicine, The School of Preclinical Medicine, Sun Yat-sen University, Guangzhou 510080, China. luobin@mail.sysu.edu.cn |
| Abstract: | Objective To improve the successful rate of operation and the livability in establishing acute myocardial ischemic rat model. Methods The successful rate of animal experiment is compared between traditional method and improved method. Results The successful rate of improved method was 90%, which was much higher than 30% in successful rate of traditional method. Conclusion The improved method may reduce the difficulty of operation remarkably and cut down the experiment expenditure, which is superior to traditional method. |
| Keywords: | rat myocardial ischemic model |
| 本文献已被 CNKI 维普 万方数据 PubMed 等数据库收录！ | |