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Hydromorphone detected in bile following hydrocodone ingestion
Authors:J I Park  G R Nakamura  E C Griesemer  T T Noguchi
Abstract:Two similar cases are reported here in which Tussionex, a preparation containing hydrocodone and phenyltoloxamine, caused or contributed to death. Toxicological analyses revealed a high concentration ratio of hydromorphone to hydrocodone in the bile in both cases. It is postulated that the finding of hydromorphone is due to the metabolism of hydrocodone.
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