| 反向遗传技术及其在猪传染性胃肠炎病毒研究中的应用 |
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| 引用本文： | 关洪鑫,李志勇,白银梅,柳纪省. 反向遗传技术及其在猪传染性胃肠炎病毒研究中的应用[J]. 中国兽医科学, 2012, 0(4): 435-440 |
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| 作者姓名： | 关洪鑫 李志勇 白银梅 柳纪省 |
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| 作者单位： | 中国农业科学院兰州兽医研究所家畜疫病病原学生物学国家重点实验室农业部草食动物疫病重点开放实验室 |
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| 基金项目： | 猪口蹄疫新型疫苗的研究和创制项目(2011AA410A211-3) |
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| 摘 要： | 对反向遗传学技术及其在RNA病毒研究中的应用进行了综述。论述了猪传染性胃肠炎病毒反向遗传技术的发展现状,并对该技术在猪传染性胃肠炎病毒的基因功能、致病机理、基因工程疫苗研究中的应用及前景等方面进行了探讨。
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| 关 键 词： | 反向遗传技术 猪传染性胃肠炎病毒 应用 |
Advances in reverse genetics technology and its application in transmissible gastroenteritis virus research |
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| GUAN Hong-xin,LI Zhi-yong,BAI Yin-mei,LIU Ji-xing. Advances in reverse genetics technology and its application in transmissible gastroenteritis virus research[J]. Chinese Veterinary Science, 2012, 0(4): 435-440 |
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| Authors: | GUAN Hong-xin LI Zhi-yong BAI Yin-mei LIU Ji-xing |
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| Affiliation: | (State Key Laboratory of Veterinary Etiological Biology/Key Laboratory of Grazing Animal Diseases of the Ministry of Agriculture/Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou 730046,China) |
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| Abstract: | Reverse genetics technology and its application in RNA virus research was reviewed in the present article.In addition,the situation of reverse genetics technology for transmissible gastroenteritis virus,application and prospect in the research of gene function,pathogenesis,engineering vaccine of transmissible gastroenteritis virus were summarized. |
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| Keywords: | reverse genetics technology transmissible gastroenteritis virus of swine application |
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