| DNA定量技术在死亡时间推断中的研究进展 |
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| 引用本文： | Lin X,Yin YS,Ji Q. DNA定量技术在死亡时间推断中的研究进展[J]. 法医学杂志, 2011, 27(1): 47-9, 53. DOI: 10.3969/j.issn.1004-5619.2011.01.014 |
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| 作者姓名： | Lin X Yin YS Ji Q |
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| 作者单位： | 南京医科大学基础医学院法医学系; |
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| 基金项目： | 江苏省教育厅科学基金项目(05KJD310140) |
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| 摘 要： | 死亡时间推断是法医病理学研究的热点及难点之一.随着分子生物学技术的发展,DNA的定量已广泛应用于死亡时间推断的研究.本文主要对机体死后不同组织和器官中DNA含量随时间的降解情况,以及单细胞凝胶电泳、Feulgen染色图像分析技术、流式细胞仪等近年来新的DNA定量技术应用于死亡时间推断研究中的进展进行了综述.
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| 关 键 词： | 法医病理学 死亡时间 综述[文献类型] DNA定量 |
Progress on DNA quantification in estimation of postmortem interval |
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| Lin Xu,Yin Ya-sha,Ji Qiang. Progress on DNA quantification in estimation of postmortem interval[J]. Journal of Forensic Medicine, 2011, 27(1): 47-9, 53. DOI: 10.3969/j.issn.1004-5619.2011.01.014 |
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| Authors: | Lin Xu Yin Ya-sha Ji Qiang |
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| Affiliation: | LIN Xu,YIN Ya-sha,JI Qiang(Department of Forensic Medicine,School of Basic Medical Science,Nanjing Medical University,Nanjing 210029,China) |
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| Abstract: | Estimation of postmortem interval(PMI) is one of the difficult problems in forensic medicine.With the development of molecular biological techniques,DNA quantification methods were widely applied in estimating PMI.The postmortem degradation of DNA in different tissues and organs was discussed in this article and the recent DNA quantitative techniques being used for estimating PMI were reviewed.These techniques included single cell gel electrophoresis,Feulgen staining image analysis,flow cytometry. |
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| Keywords: | forensic pathology postmortem interval review[publication type] DNA quantitation |
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