| 采用Identifiler系统进行全同胞关系判定的准则探讨 |
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| 作者姓名： | Zhao SM Zhang SH Li CT |
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| 作者单位： | 司法部司法鉴定科学技术研究所上海市法医学重点实验室; |
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| 基金项目： | 中央级科研院所社会公益研究资助项目(GY0902) |
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| 摘 要： | 目的 探讨采用Identifiler系统进行全同胞关系判定时共有等位基因数(IAN)和全相同基因座数(A2)的标准.方法 依据IAN和A2的有限分布,将IAN的31种取值代入已建立的判别函数,获得判定全同胞时IAN和A2的阈值,据此确定4种标准,对经Identifiler系统分型的280对全同胞和2003对无关个体对进...
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| 关 键 词： | 法医遗传学 同胞关系 共有等位基因 Identifiler系统 |
A primary study for criteria of full sibling determination with Identifiler system |
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| Zhao SM,Zhang SH,Li CT.A primary study for criteria of full sibling determination with Identifiler system[J].Journal of Forensic Medicine,2011,27(1):17-21. |
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| Authors: | Zhao Shu-min Zhang Su-hua Li Cheng-tao |
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| Institution: | ZHAO Shu-min,ZHANG Su-hua,LI Cheng-tao(Shanghai Key Laboratory of Forensic Medicine,Institute of Forensic Science,Ministry of Justice,P.R.China,Shanghai 200063,China) |
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| Abstract: | Objective To investigate the criteria of the number of identical allele(IAn) and the number of matched STR locus with 2 identical alleles(A2) for full sibling(FS) determination with Identifiler system.Methods According to the limited distribution of IAn and A2,all of the 31 potential values of IAn were substituted into the published discriminant functions to obtain the cut-off values of IAn and A2 for FS determination,and then 4 different criteria were determined to distinguish 280 FS pairs from 2 283 indiv... |
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| Keywords: | forensic genetics sibling relations identical allele Identifiler system |
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