The association between body mass index and pulmonary thromboembolism in an autopsy population |
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| Authors: | Rosenfeld Hannah E Tsokos Michael Byard Roger W |
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| Affiliation: | The University of Adelaide Medical School, Frome Road, Adelaide, SA 5005. Forensic Science SA, 21 Divett Place, Adelaide, SA 5000, Australia. Institute of Legal Medicine and Forensic Sciences, Charité University, Turmstr. 21 (Haus L), 10559, Berlin, Germany. |
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| Abstract: | Abstract: To evaluate the association between obesity and pulmonary thromboembolism (PTE) in a forensic context, 160 autopsy cases of fatal PTE were compared with age‐ and gender‐matched controls. The mean age of cases was 66 years (range 26–98 years; M/F 74:86). The mean body mass index (BMI) of cases with PTE was 30.88 (range 14.95–79.51), which was significantly higher than in the controls (mean BMI = 25.33; range 12.49–61.84) (p < 0.0001). Comparing the group with PTE with controls showed that five (3.1%) compared to 20 (12.5%) were underweight, 39 (24.4%) compared to 67 (41.88%) were of normal weight, 49 (30.63%) compared to 43 (26.88%) were overweight, 43 (26.88%) compared to 24 (15%) were obese, and 24 (15.0%) compared to six (3.75%) were morbidly obese. In each category of above‐normal BMIs, there were significantly greater numbers in the groups with PTE: overweight (p < 0.01), obese (p < 0.001), and morbidly obese (p < 0.0001). |
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| Keywords: | forensic science obesity pulmonary thromboembolism DVT BMI risk factor thrombophilia thrombus autopsy |
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