Death related to midazolam overdose during endoscopic retrograde cholangiopancreatography |
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| Authors: | Michalodimitrakis M Christodoulou P Tsatsakis A M Askoxilakis I Stiakakis I Mouzas I |
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| Institution: | Department of Forensic Pathology, University of Crete, Iraklion, Greece. |
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| Abstract: | We report a midazolam-related death that occurred during endoscopic retrograde cholangiopancreatography (ERCP). The acute intoxication due to midazolam overdose was confirmed by high-pressure liquid chromatography (HPLC) analysis of the blood samples taken from the patient in the intensive care unit (2.8 microg/ml) and postmortem (2.4 microg/ml). The case strongly emphasizes the necessity of the precautions that should be taken when midazolam is intravenously administered. |
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