听力正常人的长潜伏期听觉诱发电位

目的探索长潜伏期听觉诱发电位(auditory long latency response,ALR)潜伏期、波幅与声刺激强度间的关系和特点,并探讨其在听阈评估中的意义。方法对46名听力正常人(92耳)进行ALR测试,予受试者从70、50、30、20至10 dB nHL 5个声刺激强度顺序诱发ALR波形,标记N_1波、P_2波,得出三个观察指标(N_1波及P_2波潜伏期、N_1-P_2波幅)的数值。分析观察三个指标的变化趋势及频率差异性。结果 46名听力正常人(92耳)ALR波形的引出率均为100%。随着声刺激的降低,ALR的N_1波、P_2波潜伏期延长,N_1-P_2波幅降低。结论在适宜的条件下,ALR是一项稳定的检测技术。ALR的N_1波、P_2波潜伏期及N_1-P_2波幅与声刺激强度间的关系对ALR应用于听阈评估中有重要作用。

Research on Auditory Long Latency Response in Normal Hearing Subjects

Objective To explore the characters and the relationship among latency response, amplitude and sound stimulus intensity of auditory long latency response(ALR), and to investigate the significance of ALR applied in auditory threshold prediction.Methods Total 46 subjects(92 ears)with normal hear-ing were tested by ALR. The ALR waves of the subjects were elicited by 5 sound stimulus intensity according to the order of 70, 50, 30, 20 and 10 dB nHL. By making N1 wave and P2 wave, the values of 3 observed indexes(the latencies of N1 wave and P2 wave and N1-P2 amplitude)were obtained, and the variation trend of the observed indexes were statistically analyzed. The differences in the frequency of the indexes were observed.Results The rate of ALR waves from 46 subjects(92 ears)with normal hearing was 100%. The latencies of N1 wave and P2 wave delayed gradually and N1-P2 amplitude declined with sound stimulus intensity descending.Conclusion In suitable conditions, ALR is a stable technology for hearing thresholds prediction. The relation between sound stimulus intensity and latency of N1 wave, latency of P2 wave and N1-P2 amplitude of ALR plays an important part in auditory thresholds assessment.