Sudden infant death in a tropical environment: Singapore's experience |
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Affiliation: | 1. Departments of Forensic Medicine (SL, SJ, SKI, RB), Departments of Laboratory Medicine (PM, VT), All India Institute of Medical Sciences, Department of Surgical Disciplines (MCM), AIIMS, New Delhi, India;1. Institute of Toxicology of Federal Medico-Biological Agency, 192019 St. Petersburg, ul. Bekhtereva, 1, Russia;2. St. Petersburg State University, 199034 St. Petersburg, Universitetskaya nab., 7/9, Russia;3. Research Institute of Hygiene, Occupational Pathology and Human Ecology, Federal Medico-Biological Agency, 188663, Leningradskaya Oblast’, Vsevolozhskiy District, Kuz’molovskiy, Kapitolovo, 93, Russia;1. Department of Forensic Medicine, University of Copenhagen, Copenhagen, Denmark;2. Department of Clinical Pharmacology, Bispebjerg and Frederiksberg Hospital, Copenhagen, Denmark;3. Department of Production, Research and Innovation, Region Zealand, Denmark;4. Faculty of Health and Medical Sciences, University of Copenhagen, Denmark;5. Boston Children''s Hospital, Harvard Medical School, Boston, USA;6. Department of Endocrinology, Bispebjerg and Frederiksberg Hospital, Copenhagen, Denmark;1. Laboratory of Microbiological Monitoring and Bioremediation of Soils, All-Russia Research Institute for Agricultural Microbiology, St. Petersburg, Pushkin, Russia;2. Peter the Great St. Petersburg Polytechnic University, St. Petersburg, Russia;3. Booking.com B.V., Amsterdam, Netherlands;4. Saint-Petersburg State University, St. Petersburg, Russia;5. Institute of Chemical Biology and Fundamental Medicine, Siberian Branch, Russian Academy of Sciences, Novosibirsk, Russia;6. Laboratory of Biology and Biochemistry of Soils, V.V. Dokuchaev Soil Science Institute, Moscow, Russia |
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Abstract: | A total of 206 cases of sudden infant deaths examined at the Institute of Science and Forensic Medicine, Singapore, over a 5 year period (1989–1993) were identified to assess the pattern of sudden death in this age group, which was subdivided into the neonatal and post-neonatal periods. A total of 34% (70) of infant deaths occurred in neonatal life and the remaining 66% (136) in the post-neonatal period; 90% of the neonatal deaths were natural, of which over half were due to congenital heart disease and complications of prematurity. Unnatural deaths in this period were uncommon, there being only seven such deaths. In the post-neonatal period, unnatural deaths constituted 25% of the total with trauma and aspiration heading the list. Natural deaths in the post-neonatal period are predominantly due to infections (34%) and a group of sudden natural deaths with minimal findings (31%). The latter group may arguably represent cases of Sudden Infant Death Syndrome (SIDS). The yearly incidence of this group in our study varied between 0.08 to 0.2 per 1000 live births, which is considerably lower than the incidence quoted for Western populations. The criteria for the classification and the impact of sudden infant deaths in Asian countries are discussed. |
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