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Mass spectral and NMR spectral data of two new designer drugs with an alpha-aminophenone structure: 4'-methyl-alpha-pyrrolidinohexanophenone and 4'-methyl-alpha-pyrrolidinobutyrophenone |
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| Authors: | Westphal Folker Junge Thomas Rösner Peter Fritschi Giselher Klein B Girreser Ulrich |
| Affiliation: | 1. Landeskriminalamt Schleswig-Holstein, Sachgebiet Toxikologie/Betäubungsmittel, Mühlenweg 166, 24116 Kiel, Germany;2. Institut für Organische Chemie der Christian-Albrechts-Universität zu Kiel, Olshausenstr. 40, 24098 Kiel, Germany;3. Hessisches Landeskriminalamt, Hölderlinstr. 5, 65187 Wiesbaden, Germany;4. Pharmazeutisches Institut der Christian-Albrechts-Universität zu Kiel, Gutenbergstr. 76, 24118 Kiel, Germany |
| Abstract: | This study presents and discusses the nuclear magnetic resonance (NMR) spectroscopic and mass spectroscopic data of the new designer drug 4'-methyl-alpha-pyrrolidinobutyrophenone (MPBP) and its homolog 4'-methyl-alpha-pyrrolidinohexanophenone (MPHP) which were seized in 2004 and 2000 in Germany for the first time. The structure elucidation of the aliphatic part of MPBP was carried out by product ion spectroscopy of the immonium ion formed after electron ionization as well as with 1H and 13C NMR. Product ion spectroscopy of immonium ions again proved to be a powerful tool to determine the structure of designer drugs and to distinguish between isobaric structures of the alkyl-amino moiety. |
| Keywords: | Designer drugs α-Pyrrolidinophenone substructure Structure elucidation Mass spectral data Product ion mass spectrometry NMR spectroscopy |
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