| 表型信息SNPs在法医学中的研究进展 |
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| 引用本文： | 李忠华,扎拉嘎白乙拉,侯一平.表型信息SNPs在法医学中的研究进展[J].中国法医学杂志,2013,28(3):218-220. |
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| 作者姓名： | 李忠华 扎拉嘎白乙拉 侯一平 |
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| 作者单位： | 四川大学华西基础医学与法医学院,四川成都,610041 |
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| 摘 要： | 单核苷酸多态性(single nucleotide polymorphism,SNP),是指人群中正常个体基因组中单个碱基的变异,而能够提供个体表型信息的SNPs(phenotype informative SNPs,PISNPs)对法医学实践有重要意义。本文对PISNPs的基本概念、研究方法和其在法医学中的应用进展进行综述,并对如何加强PISNPs在法医学方面的应用提出了几点看法。
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| 关 键 词： | 法医物证学 PISNPs 全基因组关联分析 |
The research and development of PISNPs in forensic genetics |
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| Li Zhonghua,Zha Lagabaiyila,Hou Yiping.The research and development of PISNPs in forensic genetics[J].Chinese Journal of Forensic Medicine,2013,28(3):218-220. |
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| Authors: | Li Zhonghua Zha Lagabaiyila Hou Yiping |
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| Institution: | /College of Basic Medicine and Forensic Science in Sichuan University,Chegndu Scihuan 610041,China) |
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| Abstract: | Single nucleotide polymorphism is a single base pair position in genomic DNA at which different sequence alternatives exist in normal individuals in some populations.Phenotype informative SNPs are those SNPs which can provide a high probability that individual has particular phenotypes.This review offers to the reader the definition,research methods and development of PISNPs in forensic genetics and provides several suggestions to enhance the application of PISNPs. |
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| Keywords: | forensic biological evidence PISNPs GWAS |
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