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| 兰尼碱受体及其法医学意义 | |
| 引用本文： | 蒋艳伟,刘尔亮,朱少华,张磊,刘良. 兰尼碱受体及其法医学意义[J]. 中国法医学杂志, 2008, 23(1): 38-40 |
| 作者姓名： | 蒋艳伟 刘尔亮 朱少华 张磊 刘良 |
| 作者单位： | 1. 华中科技大学同济医学院法医学系,湖北,武汉,430030;天津市公安局刑科所,天津,300193 2. 天津市公安局武清分局刑警支队,天津,301700 3. 华中科技大学同济医学院法医学系,湖北,武汉,430030 |
| 摘 要： | 兰尼碱受体是心肌细胞内的钙释放通道。在心脏缺血或肥大等病理过程中兰尼碱受体的功能和数量也会发生明显变化,从而导致心肌细胞处理细胞内钙离子的能力下降或细胞内钙超载,触发致死性的室性心律失常,诱发心源性猝死。 |
| 关 键 词： | 法医病理学 兰尼碱受体 钙泵肌质网Ca2+-ATP酶 心源性猝死 致死性心律失常 |
| 文章编号： | 1001-5728(2008)01-0038-03 |
| 修稿时间： | 2007-01-12 |
Ryanodine receptor and its significance on forensic medicine |
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| JIANG Yan-wei,LIU Er-liang,ZHU Shao-hua,et al.. Ryanodine receptor and its significance on forensic medicine[J]. Chinese Journal of Forensic Medicine, 2008, 23(1): 38-40 | |
| Authors: | JIANG Yan-wei LIU Er-liang ZHU Shao-hua et al. |
| Affiliation: | JIANG Yan-wei,LIU Er-liang,ZHU Shao-hua,et al./Faculty of Forensic Medicine,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430030,China |
| Abstract: | Ryanodine receptor is a Ca2 release channel in cadiocyte.It is reported recently to the obvious change of its function and quantity in such pathological process as the myocardial ischemia and cardiac hypertrophy.These changes will affect the ability of cadiocytes processing intracellular calcium or lead to the calcium overload in the myocardial cells and then induces fatal ventricular arrhythmia,even sudden cardiac death. |
| Keywords: | Forensic pathology Ryanodine receptor Sarcopendoplasic Ca2 -ATPase Sudden cardiac death Fatal arrhythmia. |
| 本文献已被 CNKI 万方数据 等数据库收录！ | |