| 固相微萃取技术在毛发药物分析中的应用 |
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| 引用本文： | 孙英英,沈敏. 固相微萃取技术在毛发药物分析中的应用[J]. 中国司法鉴定, 2010, 0(3): 27-32,51. DOI: 10.3969/j.issn.1671-2072.2010.03.007 |
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| 作者姓名： | 孙英英 沈敏 |
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| 作者单位： | 1. 苏州大学,基础医学与生物科学学院,法医学系,江苏,苏州,215123;司法部司法鉴定科学技术研究所,上海市法医学重点实验室,上海200063
2. 司法部司法鉴定科学技术研究所,上海市法医学重点实验室,上海200063 |
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| 摘 要： | 固相微萃取（SPME）可与GC/MS、HPLC/MS等在线联用,实现分离、分析一体化的特点为其在毛发药物分析中的应用提供了可能性和良好的应用前景。本文对SPME技术在毛发中滥用药物如苯丙胺类、美沙酮、大麻、可卡因、利多卡因等及其相应代谢产物的分析研究及应用进展做一综述。
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| 关 键 词： | 固相微萃取（SPME） 毛发分析 苯丙胺类 大麻 可卡因 |
Application of Solid Phase Microextraction in Pharmaceutical Hair Analysis |
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| SUN Ying-ying,SHEN Min. Application of Solid Phase Microextraction in Pharmaceutical Hair Analysis[J]. Chinese Journal of Forensic Sciences, 2010, 0(3): 27-32,51. DOI: 10.3969/j.issn.1671-2072.2010.03.007 |
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| Authors: | SUN Ying-ying SHEN Min |
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| Affiliation: | 1.Department of forensic medicine,Institute of preclinical medicine and biological science, Soochow University,Soochow 215123,China; 2.Shanghai Key Laboratory of Forensic Science,Institute of Forensic Science,Ministry of Justice,Shanghai 200063,China) |
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| Abstract: | Solid phase microextraction（SPME）can be used on line in combination with GC/MS and HPLC/MS,and the onestep integration of separating and analyzing provide potential application in hair analysis.The paper summarizes the research and application of SPME in hair analysis of abused drugs and their metabolites,such as amphetamine-type,methadone, cannabinoids,cocaine,lidocaine,and so on. |
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| Keywords: | solid phase microextraction（SPME） hair analysis amphetamines cannabinoids cocaine |
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