脑组织与其相关分析推断死亡时间的研究进展

推断死后间隔时间(postmortem interval,PMI)一直是法医学鉴定中需要解决的重要问题之一.可用于推断PMI的尸体检材有很多种,脑组织因其独特的解剖学位置与生理功能,是推断PMI的重要检材之一.本文从三个方面将根据脑组织推断PMI的方法进行综述,包括了通过脑组织的温度、形态特点等尸体现象推断PMI;通过...

Research progress on postmortem interval inference by analysis of postmortem changes of brain tissues

The estimation of postmortem interval(PMI) is one of the most important issues in forensic medical identification. Among the many human body tissues utilized to evaluate PMI in autopsy, the brain tissue is considered to be one of the most crucial human body tissues to infer the PMI due to its special property both physiologically and anatomically. This paper reviews the use of brain tissue to infer PMI from three aspects, including postmortem changes such as temperature and morphological features;biochemical changes in components of cerebrospinal fluid and brain tissue after death such as rudimentary elements, small molecular substances, proteins, DNA, and RNA;physical traits such as biomechanical differences and electrical property in brain tissue and dura mater. Despite of the current promising progress, the application of using brain tissue in PMI estimation is still limited due to the unstable environment that affects PMI in multiple aspects and should be considered comprehensively utilizing as many as possible factors such as scene investigation, clues and cases for most accurate result. This paper reviews the existing methods of cerebral PMI inference aming to provide reference for forensic PMI inference.