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An autopsy case of imipramine poisoning
Authors:Kinoshita Hiroshi  Taniguchi Tadaaki  Kubota Akira  Nishiguchi Minori  Ouchi Harumi  Minami Takako  Utsumi Takao  Motomura Hiroyuki  Nagasaki Yasushi  Ameno Kiyoshi  Hishida Shigeru
Affiliation:Department of Legal Medicine, Hyogo College of Medicine, Hyogo, Japan. kinochin@hyo-med.ac.jp
Abstract:We present a fatal imipramine poisoning. Quantitative analysis of imipramine and its metabolite, desipramine, was performed by high-performance liquid chromatography. The concentrations of imipramine and desipramine were 18.67 microg/mL and 6.21 microg/mL in heart blood and 6.90 microg/mL and 1.77 microg/mL in the femoral venous blood, respectively. We concluded that the cause of death was due to imipramine poisoning.
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