| NF—kB对神经系统的育和调节作用 |
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| 引用本文： | Chen XP,Tao LY,Ding M. NF—kB对神经系统的育和调节作用[J]. 法医学杂志, 2002, 18(2): 112-114 |
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| 作者姓名： | Chen XP Tao LY Ding M |
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| 作者单位： | 中国医科大学法医学院,辽宁沈阳,110001 |
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| 摘 要： | 细胞核因子kB(Nuclear factor-kB,NF--kB)对感染、免疫反应以及控制细胞分化和凋亡起到广泛的作用.这些作用在神经系统中较为明显.NF-kB通常以多种亚单位形式存在于各种神经细胞中,并通过多种激活途径被激活后从胞浆易位至细胞核内发挥转录激活作用.NF-kB在对神经系统发育和抗凋亡中以及调节胶质细胞活性过程中起到至关重要的作用,对NF-kB的有关研究对法医学将具有重要的指导意义.
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| 关 键 词： | NF-kB 凋亡 法医学 |
| 文章编号： | 1004-5619(2002)02-0112-03 |
| 修稿时间： | 2001-10-16 |
Influence of NF-kappa B on the development and regulation of neural system |
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| Chen Xi-ping,Tao Lu-yang,Ding Mei. Influence of NF-kappa B on the development and regulation of neural system[J]. Journal of Forensic Medicine, 2002, 18(2): 112-114 |
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| Authors: | Chen Xi-ping Tao Lu-yang Ding Mei |
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| Affiliation: | China Medical University School of Forensic Medicine, Shenyang 110002. xipingchen@hotmail.com |
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| Abstract: | Nuclear factor-kappa B (NF-kappa B) plays an important role in controlling infection, immunity responses, cellar differentiation and apoptosis. It is of characteristics especially in neural system. NF-kappa B exist widely in neural cells and transfer from plasma into nucleolus through diversified activation passages. in addition, NF-kappa B is also a key factor in the development of the neural system, anti-apoptosis and modulating the activity of glia cells. It is of great significance in the forensic science. |
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| Keywords: | NF-kB |
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