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Monoclonal antibodies with anti-N specificity |
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| Authors: | E I Deriugina N I Drize L N Lemeneva E Iu Sadovnikova G A Udalov I L Chertkov |
| Abstract: | In this article serologic characteristics of monoclonal antibodies with anti-N specificity is given. Antibodies are directed to homologous sequence of N-form of A glycophorine (group-specific N-antigen) and B glycophorine, expressed both on N- and on M-erythrocytes. Higher titre and avidity of monoclonal antibodies with anti-N specificity in relation to erythrocytes with N-phenotype make it possible to detect N-antigen in material subjected to expert evaluation. |
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