慢性浅表性胃炎中医证型分布与幽门螺杆菌感染、胃镜像及病理表现相关性分析

目的 探讨慢性浅表性胃炎(chronic superficial gastritis,CSG)中医证型分布与幽门螺杆菌(helico-bacter pylori,Hp)感染、胃镜像及病理表现的相关性.方法 选取150例经胃镜和病理检查确诊为CSG的患者,根据中医辨证分型将其分为肝胃不和型(n=38)、脾胃湿热型(n=2...

Association of the Distribution of Traditional Chinese Medicine Syndrome Types of Chronic Superficial Gastritis with Helicobacter pylori Infection, Gastroscopic Findings, and Pathological Manifestations

Objective To investigate the association of the distribution of traditional Chinese medicine (TCM) syndrome types of chronic superficial gastritis (CSG) with Helicobacter pylori (Hp) infection, gastroscopic findings, and pathological manifestations. Methods A total of 150 patients who were diagnosed with CSG based on gastroscopy and pathological examination were enrolled, and according to their TCM syndrome type, they were divided into liver- stomach incoordination group with 38 patients, spleen- stomach damp- heat group with 22 patients, spleen- stomach deficiency group with 46 patients, stomach- Yin deficiency group with 29 patients, and gastric collateral stasis group with 15 patients. Rapid urease test and Warthin- Starry staining were used to detect Hp infection in patients, and related gastroscopic findings and pathological manifestations were collected to investigate the association of the distribution of TCM syndrome types of CSG with Hp infection, gastroscopic findings, and pathological manifestations. Results For the patients with CSG, the highest positive rate of Hp was observed in the spleen- stomach damp- heat group and the spleen- stomach deficiency group, and there was a significant difference in positive rate between these two groups and the other groups (P<0.05). White mucosa was commonly observed in patients with deficiency of spleen and stomach, clear vessel was commonly observed in patients with stomach- Yin deficiency, and mucosal roughness and granular hyperplasia were commonly observed in patients with gastric collateral stasis, with a significant difference in the distribution of TCM syndrome types (P<0.05). There was a significant difference in the degree of inflammation between the patients with different TCM syndrome types (P<0.05); mild inflammation was commonly observed in patients with incoordination between liver and stomach, moderate inflammation was commonly observed in patients with deficiency of spleen and stomach, and severe inflammation was commonly observed in patients with spleen- stomach damp- heat syndrome. Conclusion The distribution of TCM syndrome types of CSG is associated with Hp infection, gastroscopic findings, and pathological manifestations.