湿疹外洗方治疗湿热蕴肤型小儿湿疹临床观察

目的 观察湿疹外洗方治疗湿热蕴肤型小儿湿疹的临床疗效。方法 将70例符合纳入标准的湿疹患儿随机分为治疗组和对照组，每组35例（对照组脱落3例，治疗组脱落2例），治疗组采用湿疹外洗方治疗，对照组采用炉甘石洗剂治疗，连续用药2周，治疗前后对皮损面积、湿疹面积和严重度指数（eczema area and severity index， EASI）、湿热蕴肤证积分、瘙痒程度进行评价。结果 两组基于EASI的疗效、湿热蕴肤证疗效比较，差异均有统计学意义（P＜0.05），基于瘙痒评分的疗效比较，差异无统计学意义（P＞0.05）；治疗组治疗后皮损面积和湿热蕴肤证积分降低程度明显大于对照组，差异均有统计学意义（P＜0.05）。结论 湿疹外洗方可以较好地缩小湿疹皮损面积，改善中医证候和瘙痒程度。

Clinical Effect of Prescribed External Wash for Eczema in Treatment of Infantile Eczema with Damp- Heat Accumulation in the Skin

Objective To investigate the clinical effect of prescribed external wash for eczema in the treatment of infantile eczema with damp- heat accumulation in the skin. Methods A total of 70 children with eczema who met the inclusion criteria were randomly divided into treatment group and control group, with 35 children in each group (3 children in the control group and 2 in the treatment group were lost to follow- up). The children in the treatment group were given the prescribed external wash for eczema, and those in the control group were given calamine lotion; the course of treatment was 2 weeks for both groups. Skin lesion area, Eczema Area and Severity Index (EASI), score of damp- heat accumulation in the skin, and severity of pruritus were evaluated before and after treatment. Results There were significant differences in EASI and score of damp- heat accumulation in the skin between the two groups after treatment (P<0.05), while there was no significant difference in the severity of pruritus between the two groups (P>0.05). Compared with the control group, the treatment group had significantly greater reductions in skin lesion area and score of damp- heat accumulation in the skin after treatment (P<0.05). Conclusion In children with eczema, prescribed external wash for eczema can effectively reduce skin lesion area due to eczema and improve traditional Chinese medicine syndrome and the severity of pruritus.