| 正交试验优选复方青风藤巴布剂的提取工艺 |
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| 引用本文： | 林欣媛,杨转转,储晓琴,桂双英. 正交试验优选复方青风藤巴布剂的提取工艺[J]. 安徽中医药大学学报, 2017, 36(1): 85-88 |
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| 作者姓名： | 林欣媛 杨转转 储晓琴 桂双英 |
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| 作者单位： | 安徽中医药大学药学院,安徽合肥,230012;安徽中医药大学药学院,安徽合肥230012;安徽省中医药科学院药物制剂研究所,安徽合肥230012;安徽中医药大学药学院,安徽合肥230012;安徽省中医药科学院药物制剂研究所,安徽合肥230012;新安医学教育部重点实验室,安徽合肥230038 |
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| 摘 要： | 目的 优选复方青风藤巴布剂的最佳提取工艺。方法 以青藤碱、桂皮醛的含量和干膏得率为评价指标，采用正交设计法考察乙醇浓度、乙醇用量、提取时间和提取次数对提取结果的影响，确定最佳提取工艺。结果 最佳提取工艺参数为加6倍量的90%乙醇，提取3次，每次1.5 h。结论 优选的提取工艺稳定、可行。
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| 关 键 词： | 复方青风藤巴布剂 提取工艺 青藤碱 桂皮醛 正交设计 |
Optimization of Extraction Process for Compound Qingfengteng Babu Agent by an Orthogonal Test |
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| Affiliation: | 1. School of Pharmacy, Anhui University of Chinese Medicine, Anhui Hefei 230012, China; 2. Institute of Pharmaceutics, Anhui Academy of Chinese Medicine, Anhui Hefei 230012, China; 3. Key Laboratory of Xin''an Medicine, Ministry of Education, Anhui Hefei 230012, China |
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| Abstract: | Objective To investigate the optimal extraction process for Compound Qingfengteng Babu Agent.Methods The content of sinomenine and cinnamaldehyde and dry extract yield were used as assessment indices, and an orthogonal design was used to investigate the influence of alcohol concentration, alcohol amount, extraction time, and times of extraction on extraction results and determine the optimal extraction process. Results In the optimal process, extraction was performed 3 times (1.5 hours each) using 6-fold 90% alcohol. Conclusion The optimized extraction process is stable and feasible. |
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| Keywords: | Compound Qingfengteng Babu Agent Extraction process Sinomenine Cinnamaldehyde Orthogonal design |
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