| 刺囊酸微生物转化菌株的初步筛选 |
| |
| 引用本文： | 马义雯,俞年军,孙迪安,郜昭慧. 刺囊酸微生物转化菌株的初步筛选[J]. 安徽中医药大学学报, 2013, 32(1): 83-85 |
| |
| 作者姓名： | 马义雯 俞年军 孙迪安 郜昭慧 |
| |
| 作者单位： | 安徽中医学院药学院,安徽,合肥,230031;中国医学科学院,北京协和医学院药用植物研究所,北京,100193;安徽中医学院药学院,安徽,合肥,230031;中国医学科学院,北京协和医学院药用植物研究所,北京,100193 |
| |
| 摘 要： | 目的 从自然界选出不同类型的菌种,并筛选可以转化刺囊酸的菌株.方法 用微生物对刺囊酸进行转化,筛选出能转化刺囊酸的菌种,采用薄层色谱法(thin layer chromatography,TLC)和高效液相色谱法(high performance liquid chromatography,HPLC)检测转化反应的发生...
|
| 关 键 词： | 菌株 刺囊酸 微生物转化 |
Preliminary Screening for Microbial Strains Capable of Transforming Echinocystic Acid |
| |
| Affiliation: | School of Pharmacy, Anhui College of Traditional Chinese Medicine, Anhui Hefei 230031, China; 2. Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100193, China |
| |
| Abstract: | Objective To select different microbial strains and screen out those capable of transforming echinocystic acid. Methods Different microorganisms were used to transform echinocystic acid, and those capable of transforming echinocystic acid were screened out. Thin layer chromatography (TLC) and high-performance liquid chromatography (HPLC) were used to detect the transformation reaction. Results Out of 12 strains tested, 4 were capable of transforming echinocystic acid. TLC and HPLC showed that these strains transformed echinocystic acid in different ways. Conclusion The four strains capable of transforming echinocystic acid are Pestalotiopsis microspora, Helicostylum piriforme, Mucor racemosus, and Cordyceps sinensis. The transformation products of echinocystic acid can provide more valuable lead compounds for new drug development. |
| |
| Keywords: | strain echinocystic acid microbial transformation |
| 本文献已被 万方数据 等数据库收录！ |
| 点击此处可从《安徽中医药大学学报》浏览原始摘要信息 |
|
点击此处可从《安徽中医药大学学报》下载免费的PDF全文 |
|
