丹栀逍遥散加减治疗肝气郁结型尿道综合征32例

目的 观察丹栀逍遥散加减治疗肝气郁结型尿道综合征的临床疗效。方法 对32例肝气郁结型尿道综合征患者,给予丹栀逍遥散加减煎服,共服用４周。治疗4周后检测血清雌二醇水平,观察中医主症积分,评价中医证候疗效。结果 治疗4周后患者尿频尿急、尿痛、小腹酸痛、耻骨后压迫感积分和总积分（反向积分）及血清雌二醇水平显著上升(P＜0.01),中医证候总有效率为93.8%。结论 以疏肝调气立法,采用丹栀逍遥散加减治疗肝气郁结型尿道综合征疗效可靠。

Therapeutic Efficacy of Modified Danzhi Xiaoyao Powder in Treatment of Urethral Syndrome with Liver qi Stagnation: An Analysis of 32 Cases

Objective To observe the therapeutic efficacy of modified Danzhi Xiaoyao Powder in the treatment of urethral syndrome with liver qi stagnation. Methods Thirty two cases of urethral syndrome with liver qi stagnation received therapy with modified decoction of Danzhi Xiaoyao Powder for four weeks. The therapeutic efficacies were assessed based on serum estradiol levels and scores on traditional Chinese medicine (TCM) dominant syndromes. Results After four weeks of treatment, the patients showed significantly better scores on frequent micturition, urgency of urination, urodynia, aching pain of lower abdomen, and retropubic constriction as well as total scores (calculated by reverse scoring) and significantly increased serum estradiol levels (P<0.01), and the overall response rate was 93.8% in terms of TCM syndromes. Conclusion Modified Danzhi Xiaoyao Powder, which is capable of dispersing stagnated liver qi, is effective and reliable in the treatment of urethral syndrome with liver qi stagnation.