A rapid method for the determination of cocaine in brain tissue. |
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| Authors: | S P Browne C M Moore J Scheurer I R Tebbett B K Logan |
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| Affiliation: | Department of Pharmacodynamics, University of Illinois, Chicago. |
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| Abstract: | A rapid procedure is described for the extraction and analysis of brain samples for cocaine and benzoylecgonine. Human brain tissue was sectioned at autopsy, and samples were subjected to a lipase digestion, subsequent to solid-phase extraction. The distribution of cocaine and benzoylecgonine throughout different regions of the brain was determined by high-performance liquid chromatography. |
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