| 壮族人群3个STR基因座基因频率分布及其法医学应用 |
| |
| 引用本文： | 朱少建,刘超,李发贵,汪萍.壮族人群3个STR基因座基因频率分布及其法医学应用[J].中国法医学杂志,1999(1). |
| |
| 作者姓名： | 朱少建 刘超 李发贵 汪萍 |
| |
| 作者单位： | 广西壮族自治区公安厅刑事科学技术研究所!南宁，530012，广州市刑事科学技术研究所!广州，510030，广西壮族自治区公安厅刑事科学技术研究所!南宁，530012，广西壮族自治区公安厅刑事科学技术研究所!南宁，530012 |
| |
| 基金项目： | 广西壮族自治区重点科技攻关项目!9817103 |
| |
| 摘 要： | 研究3个STR基因座（D21S11、HumFGA、D19S253）在广西壮族人群中的基因频率分布及其在实际检案中的应用价值。以自制等位基因Ladder样品作为标准对照，用PCR结合PAGE技术对3个STR基因座的扩增产物进行分型。结果显示：D21S11基因座有14个等位基因，有44个基因型；HumFGA基因座有15个等位基因，40个基因型；D195253基因座有9个等位基因，23个基因型。经检验，3个STR基因座基因型分布均符合Hardy－Weinberg平衡，累计个体识别力（DP）为0．9995。3个STR基因座在壮族人群属高识别力遗传标记系统，在法医学个体识别及亲权鉴定方面有重要价值。
|
| 关 键 词： | STR基因座 D21S11基因座 HumFGA基因座 D19S253基因座 基因频率分布 个体识别 |
Allele frequency distributions of three STR loci in Chinese Zhuang ethnic group and its practical use |
| |
| Zhu Shaojian, Liu Chao, Li Fagui,et al..Allele frequency distributions of three STR loci in Chinese Zhuang ethnic group and its practical use[J].Chinese Journal of Forensic Medicine,1999(1). |
| |
| Authors: | Zhu Shaojian Liu Chao Li Fagui |
| |
| Institution: | Zhu Shaojian; Liu Chao; Li Fagui; et al. ( Guang Xi Forensic Science Insti-tute (Nan Ning 53OO12)) |
| |
| Abstract: | Allele frequency distributions of three STR loci (D21S11' HumFGA.Dl9S253) in Chinese Zhuang ethnic group were studied- The PCR products were analyzedby PAGE, followed by silver staining. Self-made allelic ladder was used as standard sizemarkers. Fourteen alleles and forty-four genotypes of D2lSl1 locus, fifteen alleles and fortygentypes of HumFGA locus, and nine alleles and twenty-three genotypes of D19S253 locuswere observed. The total discrimination P0wer of three loci was O. 9995. Our results showthat these three STR loci can be used for individual identification and paternity testingZhuang ethnic group. |
| |
| Keywords: | Short tandem repeate (STR) locus D2lS1l lcous HumFGA locus D19S253 locus Allele frequency distribution Individual identification |
| 本文献已被 CNKI 等数据库收录！ |
