Selective detection of cytomegalovirus by in situ hybridization |
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| Authors: | U Cremer |
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| Affiliation: | Abteilung Rechtsmedizin der Medizinischen Fakult?t, Rheinisch-Westf?lische Technische Hochschule Aachen, Bundesrepublik Deutschland. |
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| Abstract: | In two SIDS autopsy cases, in situ hybridization with biotin-labeled DNA probes was used to demonstrate a specific cytomegalovirus (CMV) infection in paraffin-embedded tissue sections. This technique represents a rapid, specific, and highly sensitive tool for the detection of CMV infections and is recommended for routine examination in other suspected viral infections, particularly in cases connected with SIDS. |
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