| 微波消解ICP-MS法测定人头发中24种元素的含量 |
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| 引用本文： | Zhang D,Zhuo XY. 微波消解ICP-MS法测定人头发中24种元素的含量[J]. 法医学杂志, 2011, 27(6): 425-9, 433. DOI: 10.3969/j.issn.1004-5619.2011.06.007 |
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| 作者姓名： | Zhang D Zhuo XY |
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| 作者单位： | 1. 苏州大学医学部法医学系,江苏苏州215123;司法部司法鉴定科学技术研究所上海市法医学重点实验室,上海200063
2. 司法部司法鉴定科学技术研究所上海市法医学重点实验室,上海,200063 |
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| 基金项目： | 上海市法医学重点实验室资助项目 |
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| 摘 要： | 目的建立人头发中24种无机元素的电感耦合等离子体质谱（inductively coupled plasma-mass spec-trometry,ICP-MS）分析方法。方法采用微波消解法处理样品,以铟（115In）作内标,用ICP-MS分析人头发中的24种元素含量。同时检测56例健康志愿者和10例海洛因滥用者头发中24种元素含量。结果 24种元素的方法检出限范围为0.0003~10.14μg/g,标准物质的测得值与标准值基本相符。海洛因滥用者经戒毒治疗后头发中镁、镓、钡含量下降。结论该方法灵敏度、准确度高,适用于头发中24种元素的测定。
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| 关 键 词： | 法医毒理学 电感耦合等离子体质谱 微波消解 元素 头发 |
Determination of 24 elements in human hair by ICP-MS using microwave digestion |
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| Zhang Dan,Zhuo Xian-Yi. Determination of 24 elements in human hair by ICP-MS using microwave digestion[J]. Journal of Forensic Medicine, 2011, 27(6): 425-9, 433. DOI: 10.3969/j.issn.1004-5619.2011.06.007 |
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| Authors: | Zhang Dan Zhuo Xian-Yi |
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| Affiliation: | Department of Forensic Medicine, Medical College of Soochow University, Suzhou 215123, China. Zhang.Peonia@gmail.com |
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| Abstract: | Objective To establish an inductively coupled plasma-mass spectrometry（ICP-MS） method for determination of 24 elements in human hair.Methods The samples were digested with microwave digestion instrument.ICP-MS was applied to determine 24 elements in human hair using indium（115In） as an internal standard.The established method was applied to determine element concentration in normal group（56 samples） and heroin abuse group（10 samples）.Results The limits of detection ranged from 0.000 3 g/g to 10.14 g/g.Measured value of the standard materials were basically consistent with the standard value.The contents of magnesium,gallium and barium in hair of heroin addicts decreased after rehabilitation treatment.Conclusion The method is sensitive and accurate for determination of 24 elements in human hair. |
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| Keywords: | forensic toxicology inductively coupled plasma-mass spectrometry microwave digestion elements hair |
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