| 转化生长因子β1的研究进展及其法医学应用价值 |
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| 引用本文： | 张艳,于天水,刘良,张海东,百茹峰,张振华. 转化生长因子β1的研究进展及其法医学应用价值[J]. 中国法医学杂志, 2014, 0(4): 333-336 |
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| 作者姓名： | 张艳 于天水 刘良 张海东 百茹峰 张振华 |
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| 作者单位： | 司法文明协同创新中心;中国政法大学证据科学教育部重点实验室;北市密云县检察院公诉一处;华中科技大学同济医学院法医学系; |
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| 基金项目： | 国家自然科学基金青年科学基金项目(81202383);中国政法大学青年教师学术创新团队资助项目 |
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| 摘 要： | 转化生长因子pl（transforminggrowthfactor-β1，TGF-β1）是一种具有多种生物学活性的细胞因子，存在于多种生物的不同组织中，广泛参与调节细胞增殖和分化等过程。本文综述TGF-β1的生物学特性及其在法医学中的应用价值，以期为损伤时间推断的基础研究和实际检案工作提供参考资料。
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| 关 键 词： | 法医病理学 损伤时间推断 转化生长因子β1 |
Advance in study on transforming growth factor-J51 and its applicable value in forensic medicine |
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| Affiliation: | Zhang Yan, Yu Tianshui, Liu Liang, Zhang Haidong, Bai Rufeng, Zhang Zhenhua( 1. Collaborative Innovation Center of Judicial Civilization, Beijing 100088, China ;2. Key Laboratory of Evi- dence Science, China University of Political Science and Law, Ministry of Education, Beijing 100088, China ; 3. Beijing Miyun District People＇s Procuratorate, the first Department of Public Prosecution, Beijing 101500, China ;4. Faculty of Forensic Medicine, Tongji Medical College, Huazhong University of Science and Technol- ogy, Wuhan 430030, China ) |
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| Abstract: | Transforming growth factor-β1 （ TGF-βI ） is a multifunctional cytokine which exists in various tissues of different species. It is widely involved in the regulation of cell proliferation and differentia- tion processes. Advanced study on biological characteristics of TGF-β and its applicable value in forensic medicine were reviewed in this article, which may provide reference for basic research of wound age determination and forensic practical work. |
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| Keywords: | forensic pathology wound age determination transforming growth factor-β1 |
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