Immunochemical screening: manipulation, handling and interpretation errors, exemplified by benzodiazepines |
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| Authors: | Schütz Harald Verhoff Marcel A Erdmann Freidoon Weiler Günter |
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| Affiliation: | Institut für Rechtsmedizin der Universit?t Giessen. |
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| Abstract: | The article describes problems related to immunochemical screening-tests with special regard to benzodiazepines, which are commonly used for therapeutic purposes. Focal points are adulteration, manipulation and handling of samples, the selection of cut-off-values, specificity and cross-reactivity, influence of biotransformation and frequently observed pitfalls in the interpretation of the analytical results. |
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