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The Outbreak of Fentanyl‐Related Deaths in Cook County,Illinois, Between October 2015 and December 2017: A Retrospective Study and a Comparison with Previous Data
Authors:Serenella Serinelli M.D.  Steven White M.D.   Ph.D.  Ponni Arunkumar M.D.  Dongliang Wang Ph.D.  Lorenzo Gitto M.D.
Affiliation:1. Department of Pathology, State University of New York Upstate Medical University, 750 E. Adams St., Syracuse, NY, 13210Corresponding author: Serenella Serinelli, M.D. E‐mail:;2. British Columbia Coroner's Service, 3649 Cambridge St., Vancouver, V5K1M5 BC, Canada;3. Cook County Office of Medical Examiner, 2121 W Harrison St., Chicago, IL, 60612;4. Department of Public Health and Preventive Medicine, State University of New York Upstate Medical University, 750 E. Adams St., Syracuse, NY, 13210;5. Department of Pathology, State University of New York Upstate Medical University, 750 E. Adams St., Syracuse, NY, 13210
Abstract:The National Institute on Drug Abuse has observed an increase in fentanyl deaths in the United States. One epidemic related to the abuse of fentanyl happened in Cook County in 2005–2007 (350 deaths). Another outbreak of fentanyl deaths occurred in 2015–2017 in the same area. The database of the Cook County Medical Examiner's Office was searched for cases of fentanyl deaths between 2015 and 2017: 1244 deaths were found. A comparison was performed with the previous data: an increase in the number of females was observed in 2015–2017. Also, in 2005–2007, the majority of deaths occurred among African American, while in 2015–2017, Caucasians were more involved. Within our population, some drug combinations were more common in specific demographic subgroups (male/females; Caucasian/African American; and certain age groups). The epidemiology and the most significant drug associations found at the toxicology are discussed, highlighting the usefulness of the knowledge about this outbreak for public health.
Keywords:forensic science  fentanyl  fentanyl analogs  drug overdose  toxicology  fatal  autopsy  public health
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