| Abstract: | Method of detection, purification and determination of some antidiabetic agents (ADA)--bucarban, butamid, glybenclamid, glybutide, methformine, prediane, chlorpropamide, chlocyclamide, cyclamide in biological material was developed. Microcrystalline reaction with 10% alcoholic potassium iodide, colour reactions and investigation by TLC method both native substances and nitration products were developed to identify ADA. The assay is performed by spectrophotometry. Detection limit is 2-5 mg of each substance in 50 g of the material. |
