Typing of 49 autosomal SNPs by SNaPshot in the Slovenian population |
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| Authors: | Katja Drobni
, Claus B rsting, Eszter Rockenbauer, Carmen Tomas,Niels Morling |
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| Affiliation: | a Faculty of Criminal Justice and Security, University of Maribor, Kotnikova 8, 1000 Ljubljana, Slovenia;b Forensic Science Centre, General Police Directorate, Police, Ministry of the Interior, Slovenia;c Section of Forensic Genetics, Department of Forensic Medicine, Faculty of Health Sciences, University of Copenhagen, 11 Frederik V's Vej, DK-2100 Copenhagen, Denmark |
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| Abstract: | A total of 157 unrelated individuals residing in Slovenia were typed for 49 of the autosomal single nucleotide polymorphisms (SNPs) in the SNPforID 52plex with the SNaPshot® assay. We obtained full SNP profiles in all but one individual and perfect concordance was obtained in duplicated analyses. Allele frequencies are presented for the 49 SNPs. No deviation from HWE was observed for any SNP. FIS and FST were estimated. A principal coordinate analysis performed on six populations (Slovenian, Danish, Somali, Greenland, Turkish and Chinese) showed that the Slovenian population grouped with the Danish population. The mean power of discrimination for the Slovenian population was 1.1 × 10−19, and the mean exclusion probability for trios was 99.96%. |
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| Keywords: | Autosomal single nucleotide polymorphism 49-SNP-multiplex Forensic and population genetics Slovene SNPforID |
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